Why We Created It

A better massage cream didn’t exist—so we made it.

BIOSÈME was developed by Ali Vafa MD. MPH to fill a surprising gap in post-treatment care. After years of performing thousands of Sculptra®  Aesthetic treatments , he noticed that patients were left with limited options for the essential at-home massage—most being pore-clogging oils, creams that pilled, and had no glide, making it impossible to reach the suggested massage time.


So he created a solution that elevated the ritual.


BIOSÈME is a water-activated, sculpting massage cream made for patients, by a doctor. Its soft glide, clean ingredients, and post-procedure compatibility make it the ideal choice for supporting collagen stimulation—while respecting the skin barrier.

Lightweight, non-comedogenic, and made to move with you, BIOSÈME transforms a clinical necessity into a calming daily ritual.

Why you'll love it


  • Designed specifically for post-Sculptra massage or any manual facial sculpting where lengthy massage time are important.
  • Water-activated formula glides smoothly without greasiness
  • Non-comedogenic and breakout-safe
  • Created by Dr. Ali Vafa for his own patients
  • Vegan, cruelty-free, and free of fragrance and occlusive oils